Spleen or liver? – Prospective study to evaluate the role of Splenic and Hepatic Shear Wave elastography for evaluation of portal hyperdynamic circulation.
In advanced fibrosis, liver stiffness measurements were shown to have no predictive potential for the severity of portal hypertension. We propose to test if an additional evaluation of splenic stiffness could improve the non-invasive prediction of portal hyperdynamic circulation. To compare the role of the liver (LSM) and splenic stiffness measurements (SSM) measured by shear wave elastography (SWE) in predicting the presence of esophagogastric varices (EGV) in patients with portal hypertension and to determine the correlation between the SSM and endoscopic grade of EGV.
METHODS AND MATERIALS:
LSM and variceal grade showed weak positive linear correlation (R = 0.36076, P <. 0001) whereas the SSM and variceal grade showed even weaker positive linear correlation (R = 0.20, P <. 0001). The AUC for the detection of varices was 0.77 for LSM and 0.63 for SSM respectively.
Our results are against the conventional knowledge of the significant positive correlation between LSM, SSM and variceal grading.
The poster can be viewed here: http://dx.doi.org/10.26044/ecr2020/C-14820